Menopause: the Microbiome and Nutrition

The human microbiome significantly influences health and medication responses. The immune system mediates our interaction with these microbial communities; which help regulate immune responses. Imbalances; or dysbiosis; this interplay can impact conditions like atopy; neurological and metabolic disorders; and endocrine disruption. Notably; dysbiosis during menopause may decrease gut bacterial β-glucuronidase; affecting estrogen and phytoestrogen reabsorption and distal estrogen receptors; such as those in vaginal epithelia. Advancements in research and quantitative multi-omics; enriched by AI; are paving the way for tailored lifestyle and nutritional interventions. These approaches enhance treatment efficacy and embody the promise of precision medicine to improve patient care.